Tuilleadh eolais ― Gaeilge

Is riocht measartha coitianta é Juvenile xanthogranuloma (JXG), an cineál de non‑Langerhans cell histiocytic disorder a tharlaíonn i leanaí. I thart ar 75 % de na cásanna, léirítear na loit seo laistigh den chéad bhliain den saol, agus bíonn níos mó ná 15–20 % d’othair acu ó bhreith. Cé go bhfuil JXG annamh i measc daoine fásta, is minic a tharlaíonn sé i ndaoine sna fichidí dheirfiúnta go dtí na tríochaidí, agus ní bhíonn ach lot amháin ag formhór na n‑othar fásta. Go cliniciúil, feictear sé mar chnapáin nó cnapáin ghnólachta aonair nó iolracha buí‑oráiste‑donn, go príomha ar an duine, muineál, agus comhlacht uachtair. Tá loit béil neamhchoitianta, ach d’fhéadfadh siad a bheith le feiceáil mar chnap buí ar thaobh an teanga nó in áit eile sa bhéal, rud a d’fhéadfadh a bheith mar thoradh ar othrais agus fuiliú. De ghnáth ní bhíonn loit chraicinn ina chúis le hairíonna, agus imíonn siad ina n‑aonar thar roinnt blianta. Cé go bhfuil sé annamh, is í baint súl an tsaincheist is coitianta lasmuigh den chraiceann, agus leantann scamhóg i ndiaidh sin. Ní bhíonn tionchar ag Ocular JXG ach ar shúil amháin de ghnáth, agus tarlaíonn sé i níos lú ná 0,5 % d’othair, cé go mbíonn loit chraicinn iolracha ag thart ar 40 % díobh siúd a bhfuil baint súl acu nuair a dhéantar diagnóis orthu.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.

Is galar neamhchoitianta, neamhurchóideach iad Juvenile xanthogranulomas (JXGs), atá mar chuid de chatagóir níos mó de non‑Langerhans cell histiocytoses. Is gnách go dtaispeánann siad mar chnapshuim dearg nó buí amháin nó níos mó, a fhaightear go minic ar an gceann nó ar an muineál. Formhór na JXG ag teacht chun cinn le linn na breithe nó laistigh den chéad bhliain dá saol. Cé go bhfuil sé neamhghnách, uaireanta féadann siad dul i bhfeidhm ar limistéir lasmuigh den chraiceann, agus is rud a luadh i litríocht atá ann cheana féin. Go ginearálta, imíonn JXG ar an gcraiceann ina n-aonar agus de ghnáth ní bhíonn cóireáil de dhíth orthu.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.